Mitoptosis: Different Pathways for Mitochondrial Execution
نویسندگان
چکیده
منابع مشابه
Mitoptosis, a Novel Mitochondrial Death Mechanism Leading Predominantly to Activation of Autophagy
Please cite this paper as: Jangamreddy JR, Los MJ. Mitoptosis, a Novel Mitochondrial Death Mechanism Leading Predominantly to Activation of Autophagy. Hepat Mon. 2012;12(8): e6159. DOI: 10.5812/hepatmon.6159 Implication for health policy/practice/research/medical education: The manuscript provides insight into the recently-discovered new form of cell death that may co-exist with autophagy, apop...
متن کاملDifferent import pathways through the mitochondrial intermembrane space for inner membrane proteins.
Earlier work on the protein import system of yeast mitochondria has identified two soluble 70 kDa protein complexes in the intermembrane space. One complex contains the essential proteins Tim9p and Tim10p and mediates transport of cytosolically-made metabolite carrier proteins from the outer to the inner membrane. The other complex contains the non-essential proteins Tim8p and Tim13p as well as...
متن کاملReview Mitochondrial apoptotic pathways
Apoptosis or programmed cell death (PCD) is a physiological process characteristic of pluricellular organisms leading to self-destruction of the cell. It is therefore involved in development, homeostasis and host defense. However, a significant difference has been shown between mammalian cell apoptosis and non-mammalian cell apoptosis: mitochondria are implicated only in the former. Execution o...
متن کاملMultiple pathways for sorting mitochondrial precursor proteins.
Mitochondria import hundreds of different precursor proteins from the cytosol. More than 50% of mitochondrial proteins do not use the classical import pathway that is guided by amino-terminal presequences, but instead contain different types of internal targeting signals. Recent studies have revealed an unexpected complexity of the mitochondrial protein import machinery and have led to the disc...
متن کاملEconazole Nitrate Induces Apoptosis in MCF-7 Cells via Mitochondrial and Caspase Pathways
Econazole nitrate (EN), a synthetic compound, is now in use as a routine antifungal drug. EN was shown to have antitumor effect, the tumor cell killing mechanisms, however, remain unclear. In this research, the apoptosis-inducing effect of EN on MCF-7 cells was investigated. The results showed that EN inhibited the proliferation of MCF-7 cells in a time- and dose-dependent manner by MTT method ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Autophagy
سال: 2007
ISSN: 1554-8627,1554-8635
DOI: 10.4161/auto.3924